New organism and enzyme development, as well as process development, optimization and up-scaling:

Gene engineering

l Efficient expression of peptide-protein genes(protein engineering)

l Directed evolution and site-mutagenesis of enzyme (enzyme engineering)

l Modification and reconstruction of metabolic pathways(metabolic engineering)

l Transfer of whole genome or chromosome (genome engineering)

Synthetic biology

l Synthesis, simplification and reconstitution of chassis organism and their genomes to serve as platforms for the operation of various biological elements, cassettes and systems for the reconstitution and construction of strains

l Synthesis, modification and modularization of bio-macromolecules (such as nucleic acid and proteins), optimization and modification of enzyme functions to achieve protein engineering.

l Optimization of synthetic pathways using artificial elements, using different strength promoters or inter-genic sequences to optimize gene expression for the purpose of optimizing metabolic pathways and improving product yield.

l Based on the analysis of known enzymatic reactions and chemical retro-synthesis, we realize the design of synthetic pathways that do not exist in nature